In this article, we demonstrate that conolidine, a pure analgesic alkaloid Utilized in traditional Chinese drugs, targets ACKR3, thereby providing additional evidence of the correlation among ACKR3 and pain modulation and opening substitute therapeutic avenues to the procedure of Persistent ache. We demonstrated that, in contrast to classical opioid https://what-is-chronic-pain88753.like-blogs.com/31110422/what-does-what-is-conolidine-mean