And finally, clonidine improves neuraxial opioids and, in combination with fentanyl, interacts in an additive way, which might reduce the dose of every ingredient by sixty% for postoperative analgesia. Clonidine treats high blood pressure by stimulating αtwo receptors in the brainstem, which decreases peripheral vascular resistance, lowering blood pressure. https://williame495nsr2.wikibestproducts.com/user